PERT Shortage
PERT (Pancreatic Enzyme Replacement Therapy) overview:
SPS overview to support prescribing and ordering of available pancreatic enzyme replacement therapies, with links to NatPSA and individual supply entry posts for affected products. The following individual posts have been updated: Pancrex V products
Resources for pharmacies:
- Latest position statement on the PERT shortage, published 11th April 2025 for health professionals
- Surrey Heartlands ICB guidance
- Community Pharmacy Surrey & Sussex PERT shortage guidance
Resources for patients:
There is also information and resources available for patients.
Pancreatic Cancer UK’s patient information on how to deal with the PERT shortages
Supply of Unlicensed PERT products:
A CPE article on the supply of unlicensed PERT preparations with visuals regarding what correctly written and incorrectly written prescriptions for the imported products look like, is available here: https://cpe.org.uk/our-news/supply-of-unlicensed-pert-preparations/
Local Guidance:
Please find below a summary of the current supply challenges with Pancreatic Enzyme Replacement Therapy (PERT) and local guidance which provides advice and actions for prescribers, patients and community pharmacy/dispensing practices. Please cascade this information to all staff involved in the prescribing and dispensing of PERT products.
